Fentanyl, sufentanil, alfentanil and myocardial function.
نویسندگان
چکیده
REFERENCE 1 Miller DR, WellwoodM, Teasdale SJ et al. Effects of anaesthetic induction on myocardial function and metabolism: a comparison of fentanyl, sufentanil and alfentanil. Can J Anaes 1988; 35: 219-33. on-line pressure-volume loop eapability to pin-point more precisely ventricular cad systole for future studies. Finally, although the negative effects on cardiac function were observed, to varying degrees, with all three narcotics, the adverse effects on myocardial metabolism (and the greatest decrease in diastolic compliance) were observed only after alfentanil. The fact that all three groups were ventilated with equal positive pressure yet showed different diastolic compliance slopes suggests ischaemic-indueed changes. This was supported by adverse metabolic changes in the alfentanil group. tn conclusion, we believe that anaesthetic induction with the narcotic agents studied produced small but significant alterations in myocardial fitnction and metabolism (the latter in the alfentanil group) in patients undergoing elective coronary bypass surgery. Patients with impaired ventricular function and those who have acute ischaemia may have a mare pronounced response to narcotic induction. Caution should be exercised under these circumstances.
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ورودعنوان ژورنال:
- Canadian journal of anaesthesia = Journal canadien d'anesthesie
دوره 36 2 شماره
صفحات -
تاریخ انتشار 1989